Windows 10 - USB Mouse disconnects or loses power randomly. You hear the sound of the USB device being unattached. How to restart a usb port or connection.

Original Workarounds here
https://support.microsoft.com/en-us/help/817900/usb-port-may-stop-working-after-you-remove-or-insert-a-usb-device

http://www.tomshardware.com/answers/id-1783536/usb-ports-disconnecting-reconnecting.html

At the end of the day the only thing that really worked for me was restating the machine, or restarting the Chipset Host Controller under the Universal Serial Bus Controllers

• How to restart a usb port or connection
• Go to Control Panel>Device Manager>Universal Serial Bus Controllers
• Each USB port will have a corresponding Host Controller
• For each one, right click and disable, then right click and enable
• How to disable USB Suspend Power Settings
• Scroll to the right and type 'Power Options' in the search field and click on it.
• Click 'Change plan setting' on your chosen plan.
• Click 'Change advanced power setting' on your chosen plan.
• Find 'USB settings' and open.
• Find 'USB selective suspend setting' and change it to disabled.